Publications
Find an abstract and a link to most of the publications produced by Nordic Bioscience
Find an abstract and a link to most of the publications produced by Nordic Bioscience
Objective Gender is a risk factor in the onset of osteoarthritis (OA). The aim of the study was to investigate gender differences in contact area (CA) and congruity index (CI) in the medial tibiofemoral (MTF) joint in 2 different cohorts, quantified automatically from magnetic resonance imaging (MRI...
Summary: Early prognosis of osteoporosis risk is not only important to individual patients but is also a key factor when screening for osteoporosis drug trial populations. We present an osteoporosis fracture risk score based on vertebral heights. The score separated individuals who sustained fractur...
July 22, 2011
Journal:
Osteoporos Int.
Author:
Lillholm M, Ghosh A, Pettersen PC, de Bruijne M, Dam EB, Karsdal MA, Christiansen C, Genant HK, Nielsen M
Background: Aortic calcification is a major risk factor for death from cardiovascular disease. We investigated the relationship between mortality and the composite markers of number, size, morphology and distribution of calcified plaques in the lumbar aorta. Methods: 308 postmenopausal women aged 4...
November 10, 2010
Journal:
BMC Cardiovasc Disord
Author:
Nielsen M, Ganz M, Lauze F, Pettersen PC, Clarkson TB, Dam EB, Christiansen C, de Bruijne M, Karsdal MA
INTRODUCTION: At present, no disease-modifying osteoarthritis drugs (DMOADS) are approved by the FDA (US Food and Drug Administration); possibly partly due to inadequate trial design since efficacy demonstration requires disease progression in the placebo group. We investigated whether combinations ...
July 24, 2009
Journal:
Arthritis Res Ther
Author:
Dam EB, Loog M, Christiansen C, Byrjalsen I, Folkesson J, Nielsen M, Qazi AA, Pettersen PC, Garnero P, Karsdal MA
OBJECTIVE:Osteoarthritis (OA) is the most common form of arthritic disease, and it is a major cause of disability and impaired quality of life in the elderly. OA is a complex disease of the entire joint, including bone and cartilage, thereby presenting alternative approaches for treatment. This revi...
June 16, 2008
Journal:
Osteoarthritis Cartilage
Author:
Karsdal MA, Leeming DJ, Dam EB, Henriksen K, Alexandersen P, Pastoureau P, Altman RD, Christiansen C
The objective of this study was to quantitatively assess the surface curvature of the articular cartilage from low-field magnetic resonance imaging (MRI) data, and to investigate its role in populations with varying radiographic signs of osteoarthritis (OA), cross-sectionally and longitudinally. The...
June 6, 2008
Journal:
Magn Reson Med
Author:
Folkesson J, Dam EB, Olsen OF, Karsdal MA, Pettersen PC, Christiansen C
RATIONALE AND OBJECTIVES: Cartilage loss as determined by magnetic resonance imaging (MRI) or joint space narrowing as determined by x-ray is the result of cartilage erosion. However, metabolic processes within the cartilage that later result in cartilage loss may be a more sensitive assessment meth...
October 14, 2007
Journal:
Acad Radiol
Author:
Qazi AA, Dam EB, Nielsen M, Karsdal MA, Pettersen PC, Christiansen C
OBJECTIVE: Cartilage loss as determined either by magnetic resonance imaging (MRI) or by joint space narrowing in X-rays is the result of cartilage erosion. However, metabolic processes within the cartilage that later result in cartilage loss may be a more accurate assessment method for early change...
May 10, 2007
Journal:
Osteoarthritis Cartilage
Author:
Qazi AA, Folkesson J, Karsdal MA, Christiansen C, Dam EB
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