Find an abstract and a link to all the publications produced by Nordic Bioscience
OBJECTIVE: Characterize biomarkers measuring extracellular matrix turnover of inflamed osteoarthritis synovium. METHODS: Human primary fibroblast-like synoviocytes and synovial membrane explants (SMEs) treated with various cytokines and growth factors were assessed by C1M, C3M, and acMMP3 in the co...
February 10, 2016
Journal:
Biomarkers
Author:
Bay-Jensen AC, Karsdal MA, Ladel C, Christiansen TG, Siebuhr AS, Kjelgaard-Petersen CF
Objective: The specific degradation of type II collagen and aggrecan by matrix metalloproteinase (MMP)-9, -13 and ADAMTS-4 and -5 (aggrecanase-1 and -2) in the cartilage matrix is a critical step in pathology of osteoarthritis (OA). The aims of this study were: i) To investigate the relative contrib...
April 24, 2015
Journal:
PLoS One
Author:
He Y, Zheng Q, Jiang M, Christiansen TG, Kassem M, Karsdal MA, Bay-Jensen AC
The aim of this study was to enable measurement of cartilage formation by a novel biomarker of type II collagen formation. The competitive enzyme-linked immunosorbent assay (ELISA) Pro-C2 was developed and characterized for assessment of the beta splice variant of type II procollagen (PIIBNP). This ...
October 17, 2014
Journal:
Int J Mol Sci
Author:
Gudmann NS, Wang J, Hoielt S, Chen P, Siebuhr AS, He Y, Christiansen TG, Karsdal MA, Bay-Jensen AC
Search and find publications that we have published.
Please don't hesitate to contact us if you have any questions or other inquiries.
We use cookies on our site to enable essential services and functionalities, and collect data in regards to visitor information to provide the best possible experience. By using our website, you agree to our Privacy Policy and our cookies usage. Cookie Policy Privacy Statement
