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Objective: To investigate acute changes in biochemical markers of cartilage turnover in response to moderate intensity exercise with and without joint impact in humans with knee osteoarthritis. Design: We conducted a randomized, cross-over, exploratory clinical study. Twenty subjects with knee osteo...
July 29, 2021
Journal:
Osteoarthritis Cartilage
Author:
Bjerre-Bastos JJ, Andersen JR, Karsdal MA, Bay-Jensen AC, Mackey AL, Byrjalsen I, Bihlet AR, Boesen MP, Nielsen Bay H
Abstract Purpose: To investigate acute changes in biochemical markers of bone and cartilage turnover in response to moderate intensity exercise with and without joint impact in healthy human subjects. Methods: A randomized, cross-over, exploratory, clinical study was conducted. Twenty healthy subjec...
June 22, 2021
Journal:
Eir K Appl Physiol
Author:
Bjerre-Bastos JJ, Nielsen Bay H, Karsdal MA, Bihlet AR, Boesen MP, Inger B, Andersen JR, Mackey AL, Thudium CS
OBJECTIVES: To investigate the association between magnetic resonance imaging (MRI), macroscopic and histological assessments of synovitis in end-stage knee osteoarthritis (KOA). METHODS: Synovitis of end-stage osteoarthritic knees was assessed using non-contrast-enhanced (CE), contrast-enhanced ma...
October 11, 2016
Journal:
Osteoarthritis Cartilage
Author:
Riis RG, Gudbergsen H, Simonsen O, Henriksen M, Al-Mashkur N, Eld M, Petersen KK, Kubassova O, Bay Jensen AC, Damm J, Bliddal H, Arendt-Nielsen L, Boesen MP
OBJECTIVE:Synovitis is a frequent condition in knee osteoarthritis (KOA) and has been associated with pain. This study investigated the links between the pressure hyperalgesia, the clinical pain, the degree of the synovitis, inflammatory biomarkers, and tissue-specific biomarkers in KOA patients. M...
December 2, 2015
Journal:
Clin J Pain
Author:
Petersen KK, Siebuhr AS, Graven-Nielsen T, Simonsen O, Boesen MP, Gudbergsen H, Karsdal MA, Bay-Jensen AC, Arendt-Nielsen L
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