Type III, IV, and VI Collagens Turnover in Systemic Sclerosis - a Longitudinal Study

Abstract

Tissue turnover, especially in the skin, is altered in systemic sclerosis (SSc), leading to tissue accumulation. The objective was to examine type III, IV, and VI collagens turnovers in SSc and investigate longitudinal alterations in relation to modified Rodnan Skin Score (mRSS). We included patients fulfilling the 2013 ACR/EULAR criteria for SSc (limited cutaneous [lcSSc,

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Categories

April 28, 2020

Journal:
Sci Rep

Author:
Juhl P, Bay-Jensen AC, Hesselstrand R, Siebuhr AS, Wuttge DM

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