Find an abstract and a link to most of the publications produced by Nordic Bioscience
Emerging evidence suggests that altered components and posttranslational modifications of proteins in the extracellular matrix (ECM) may both initiate and drive disease progression. The ECM is a complex grid consisting of multiple proteins, most of which play a vital role in containing the essential...
May 15, 2015
Journal:
Am J Physiol Gastrointest Liver Physiol
Author:
Karsdal MA, Manon-Jensen T, Genovese F, Kristensen JH, Nielsen MJ, Brandt-Hansen NU, Bay-Jensen AC, Bager CL, Krag A, Krarup H, Leeming DJ, Schuppan D, Blanchard AD, Bülow Sand JM
Background: Nearly 45% of all deaths are associated with chronic fibroproliferative diseases, of which the primary characteristic is altered remodelling of the extracellular matrix. A major difficulty in developing anti-fibrotic therapies is the lack of accurate and established techniques to estimat...
August 5, 2014
Journal:
Aliment Pharmacol Ther.
Author:
Karsdal MA, Krarup H, Christensen PB, Gerstoft J, Leeming DJ, Weis N, Schaffalitzky de Muckadell OB, Krag A, Bülow Sand JM
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