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The heterogeneous nature of osteoarthritis (OA) and the need to subtype patients is widely accepted in the field. The biomarker CRPM, a metabolite of C-reactive protein (CRP), is released to the circulation during inflammation. Blood CRPM levels have shown to be associated with disease activity and ...
March 22, 2021
Journal:
Sci Rep
Author:
Bay-Jensen AC, Byrjalsen I, Andersen JR, Riis BJ, Christiansen C, Michaelis M, Guehring H, Ladel C, Karsdal MA, Bihlet AR
Importance: Sprifermin is under investigation as a disease-modifying osteoarthritis drug. Objective: To evaluate the effects of sprifermin on changes in total femorotibial joint cartilage thickness in the more symptomatic knee of patients with osteoarthritis. Design, setting, and participants: FOR...
October 8, 2019
Journal:
JAMA.
Author:
Hochberg MC, Guermazi A, Guehring H, Aydemir A, Wax S, Reinstrup Bihlet A, Byrjalsen I, Eckstein F, Fleuranceau-Morel P, Andersen JR
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