Biomarker name
Assay description
Function
TIM-2
Specific fragment of MMP-12-mediated degradation of titin (Muscle isoform)
Cardiac remodeling
TSP-2
N-terminal Thrombospondin 2
N/A
U-CTX-II
MMP9-or 13-degradation fragment of type II collagen
Cartilage and fibrocartilage degradation and remodeling
uPerla
Neo-epiotpe of ADAMTS mediated degradation of perlecan
ECM remodeling
VCANM
Neo-epitope of MMP-8,12 mediated degradation of versican
ECM remodeling
VIM
Neo-epitope of MMP-2 and MMP-8 mediated degradation of Vimentin
N/A
vWF-A
Neo-epitope of ADAMTS13 mediated degradation of von willebrand factor
von Willebrand factor activation
vWF-N
Released N-terminal pro-peptide of von willebrand factor
von Willebrand factor activation
X-FIB
Neo-epitope of plasmin mediated degradation of cross-linked fibrin (sandwich assay)
Clot resolution

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