Bone
21. Jan 2004
Measurement of tumor load and distribution in a model of cancer-induced osteolysis: a necessary precaution when testing novel anti-resorptive therapies
The Arguello model of cancer metastasis to bone has been used extensively to study breast cancer-induced osteolytic disease. The effects of therapy on skeletal disease and on tumour burden in soft organs are traditionally measured using radiography and/or time-consuming histomorphometry, respectivel…
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Authors:
- Amhlaoibh RN,
- Hoegh-Andersen P,
- Brünner N,
- Sørensen A,
- Winding B,
- Holst-Hansen C,
- Karsdal MA,
- Engsig MT,
- Delaissé JM,
- Heegaard AM,