Oncology, Breast, Extracellular Matrix Research
3. Aug 2015
Collagen degradation products measured in serum can separate ovarian and breast cancer patients from healthy controls: A preliminary study
BACKGROUND:
During cancer the otherwise tightly controlled homeostasis of the extracellular matrix (ECM) is disturbed. The protein composition changes, the ECM stiffens and increased levels of proteases are secreted. The combination of these processes result in release of specific protein fragments…
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Authors:
- Bager CL,
- Willumsen N,
- Leeming DJ,
- Smith V,
- Karsdal MA,
- Dornan D,
- Bay-Jensen AC,