Oncology, Pancreas
6. Nov 2013
Extracellular matrix specific protein fingerprints measured in serum can separate pancreatic cancer patients from healthy controls
BACKGROUND:
Pancreatic cancer (PC) is an aggressive disease with an urgent need for biomarkers. Hallmarks of PC include increased collagen deposition (desmoplasia) and increased matrix metalloproteinase (MMP) activity. The aim of this study was to investigate whether protein fingerprints of specifi…
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Journal:
Authors:
- Willumsen N,
- Bager CL,
- Leeming DJ,
- Smith V,
- Karsdal MA,
- Dornan D,
- Bay-Jensen AC,
Oncology, Bone
27. Jun 2008
Does increased local bone resorption secondary to breast and prostate cancer result in increased cartilage degradation?
BACKGROUND:
Breast and prostate cancer patients often develop lesions of locally high bone turnover, when the primary tumor metastasizes to the bone causing an abnormal high bone resorption at this site. The objective of the present study was to determine whether local increased bone turnover in br…
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Journal:
Authors:
- Leeming DJ,
- Byrjalsen I,
- Qvist P,
- Koizumi M,
- Lynnerup N,
- Fregerslev M,
- Sørensen MG,
- Christiansen C,
- Karsdal MA,