Rheumatology, Osteoarthritis
29. Jul 2018
Tofacitinib and TPCA-1 Exert Chondroprotective Effects on Extracellular Matrix Turnover in Bovine Articular Cartilage Ex vivo.
OBJECTIVE:
Currently, there are no disease-modifying osteoarthritis drugs (DMOADs) approved for osteoarthritis. It is hypothesized that a subtype of OA may be driven by inflammation and may benefit from treatment with anti-inflammatory small molecule inhibitors adopted from treatments of rheumatoid…
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Journal:
Authors:
- Kjelgaard-Petersen CF,
- Sharma N,
- Kayed A,
- Karsdal MA,
- Mobasheri A,
- Hägglund P,
- Bay-Jensen AC,
- Thudium CS,