Figure 1. 
Various immune-mediated liver diseases have different collagen profiles.[1]

In a study conducted, patients diagnosed with different immune-mediated liver diseases such as autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) were examined using a range of Nordic Bioscience's liver function biomarkers.[1Specifically, PRO-C3, a marker of tissue formation, and BGM, C3M and C4M, markers of tissue breakdown, were assessed.

Additionally, patients with ulcerative colitis (UC), a frequently coexisting condition with immune-mediated liver disease, were included for comparison. The results of this investigation unveiled distinct collagen profiles across various immune-mediated liver diseases (Figure 1). 

The identification and characterization of these collagen profiles hold promise for tailoring targeted treatments and advancing personalized medicine approaches for patients with different immune-mediated liver diseases.

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