Tissue fibrosis is a key event in SSc, and quantification of fibrosis can provide a unique insight into structural and functional changes in the disease pathogenesis.

In addition, one of the key features of Nordic Bioscience's biomarkers is the trajectories and association to modified Rodnan skin score (mRSS, a semiquantitative score, ranging from 0 to 3, correlating with histological skin thickness), as illustrated in Figure 1.

Figure 1. mRSS and Fibrotic Index 
 Browse our list of systemic sclerosis biomarkers

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