Figure 2. Biomarkers of SSc progression

A balanced extracellular matrix (ECM) is necessary to preserve organ integrity and tissue homeostasis.

In SSc, as shown in Figure 2, this balance is altered, and the fibrosis biomarkers (PRO-C3 and PRO-C6) are associated with disease progression (10% decline in FVC%, or increased mRSS >25% during a one-year clinical follow-up).

At the same time, tissue degradation biomarkers were associated with stable disease.

This has been shown in a study published in The Lancet, in 2021.

Please don't hesitate to contact us if you have any questions or other inquiries.

Are you interested in learning more about Nordic Bioscience?
Enter your information in the form and a representative will contact you shortly.

By submitting this form you agree to our terms and conditions.